Keep an eye on individuals for signs of urinary retention or diminished gastric motility when OxyContin is used concomitantly with anticholinergic drugs
Tell woman individuals of reproductive probable that OXYCONTIN could potentially cause fetal hurt and to tell their healthcare company of a identified or suspected pregnancy [see Use In Certain Populations].
The oxycodone in OxyContin may bring about spasm in the sphincter of Oddi. Opioids may perhaps bring about increases within the serum amylase. Keep an eye on clients with biliary tract disease, which includes acute pancreatitis.
If concomitant use is important, take into consideration dosage reduction of OXYCONTIN until eventually stable drug effects are achieved. Check individuals for respiratory melancholy and sedation at Repeated intervals.
Observational research have shown that concomitant utilization of opioid analgesics and benzodiazepines enhances the hazard of drug-associated mortality as compared to use of opioid analgesics alone.
Alert individuals never to drive or operate unsafe machinery Except They are really tolerant to the effects of OxyContin and understand how they'll react on the medication.
Oxycodone can move into breast milk and may harm a nursing baby. You should not breast-feed when you are utilizing this medication.
There is restricted working experience with conversion from transdermal fentanyl to OXYCONTIN in pediatric individuals 11 many years and more mature. If switching from transdermal fentanyl patch to OXYCONTIN, be sure that the read more patch has long been taken out for at least 18 hrs ahead of starting off OXYCONTIN.
Neonatal Opioid Withdrawal Syndrome Extended usage of OxyContin all through pregnancy may lead to withdrawal inside the neonate. Neonatal opioid withdrawal syndrome, unlike opioid withdrawal syndrome in Grownups, can be lifetime-threatening Otherwise recognized and taken care of, and demands administration In accordance with protocols developed by neonatology professionals.
To cut back the potential risk of respiratory despair, correct dosing and titration of OxyContin are crucial. Overestimating the OxyContin dosage when changing people from A further opioid item can lead to a lethal overdose with the 1st dose.
Adrenal Insufficiency Conditions of adrenal insufficiency have been documented with opioid use, extra often next larger than a person month of use. If adrenal insufficiency is suspected, validate the prognosis with diagnostic tests without delay.
g., main melancholy). The likely for these challenges must not, nonetheless, stop the right management of soreness in any given client. People at enhanced risk can be prescribed opioids like OxyContin, but use in this kind of people necessitates intense counseling about the challenges and right utilization of OxyContin along with intense monitoring for indications of click here habit, here abuse, and misuse.
Assess Every single patient's hazard for opioid dependancy, abuse, or misuse just before prescribing OxyContin, and observe all individuals obtaining OxyContin for the event of those behaviors and ailments. Pitfalls are greater in sufferers with a private or loved ones history of substance abuse (which includes drug or Liquor abuse or habit) or psychological disease (e.
Keep an eye on patients having a background of seizure Diseases for worsened seizure Manage in the course of OxyContin therapy.